Research activities of Normal Physiology

Over the past year, the staff of the department received 1 patent from the Russian Federation for an invention. 15 articles were published, 7 of them in journals, 8 in collections of scientific articles; in the CIS - 6 (in journals of the Russian Federation), in the far abroad - 1, electronic editions - 4. Over the years of the department's existence, according to the results of scientific research, employees have defended 4 doctoral and 28 master's theses.

Among the main activities of the department, much attention has always been paid to the scientific work of its employees. Many scientists of the department are widely known for their scientific developments in various fields of physiology. The results of scientific developments on the physiology of autonomic ganglia (Prof. I.A. Bulygin) and the physiology of thermoregulation (Prof. V.A. Gurin) were awarded the State Prizes of the USSR and Belarus.

More than half of teachers have academic degrees, including doctors of medical sciences and the corresponding member of the National Academy of Sciences of Belarus, and 1 honored scientist.

Scientific and Pedagogical School of Physiologists

The department researches the neurophysiological foundations of the formation of reactions of the cardiovascular and visual systems to sensory signals. The head of this direction is Professor A.I. Kubarko. Based on the results of these studies, the staff of the department defended dissertations, published monographs and articles in Belarusian and foreign journals and collections of scientific papers. Instructions for the comprehensive assessment and use of indicators of sensory sensitivity of the visual system for differential diagnosis of demyelinating and ischemic optic neuropathies were prepared and approved by the Ministry of Health of the Republic of Belarus, which, together with other methods developed at the department, are used in clinical practice.

Currently, research is being carried out on the mechanisms of functioning of a hypothetical brain error detector, with the participation of which erroneous actions committed by a person are detected and corrected. This occurs with erroneous eye movements observed during saccades. In particular, these errors are detected during reading when the eyes move quickly from the end of the read line to a new one. Contrary to the popular belief that ballistic movements, which include saccadic eye movements, are not corrected, we found that these movements, if they are erroneous, are instantly detected by a brain detector, interrupted, and corrected by corrective saccades.

Within the framework of the Republican scientific program “Convergence”, the department carries out joint scientific research and the Research Institute of Physics of the National Academy of Sciences of Belarus, as well as joint work with the Belarusian State University and the Lublin Polytechnic University (Poland). It is planned on the basis of the results of studies of neurophysiological mechanisms that determine the light sensitivity of the visual system and its dependence on the state of hemodynamics in the vessels of the retina of the eye and brain, to develop methods, equipment, and software for the early detection of pathology of the vessels of the visual system and the human brain.

The department also researches the state of health of young people in the process of education and the development of methods and means for correcting the functional systems of the body. The head of this direction is Professor V.A. Pereverzev.

The studies carried out made it possible to establish the facts of an unsatisfactory level of physical health, both in boys (60%) and in girls (in 80%) due to a decrease in their muscle strength and reserves of the cardiorespiratory system. Long-term impairment of the state of cognitive functions and glucose metabolism was shown in students who consume alcoholic beverages, compared with teetotalers. The developed physical culture and health-improving technology of individual rationing of the intensity of physical activity when performing cyclic exercises by students, depending on their physical condition, has made it possible to increase the level of students' health. The facts of the negative effect of alcohol on mental performance and glucose metabolism in a sober person within 1-4 weeks significantly supplemented the evidence base on the negative effects of ethanol.

Based on the results of these studies, a Ph.D. thesis was defended, monographs and articles were published in domestic and foreign journals and collections.

The department has repeatedly been the organizer of international and republican conferences and congresses, in particular, the department was one of the organizers of the III International conference “Signaling mechanisms of regulation of physiological functions” and the XIV Congress of the Belarusian Society of Physiologists.

Invention patents received:

“Method for determining the concentration of chromophores in biological tissue.” Authors: Lysenko S.A., Kugeiko M.M., Firago V.A., Kubarko A.I. RF No. 2012 132915/28 (052215).

“A method for inhibiting radiation-induced changes in platelet aggregation capacity caused by γ-irradiation.” Authors: Konoplya E.F., Lobanok L.M., Bulanova K.Ya. Patent of the Republic of Belarus by application No. a20091688, 08/20/2014.

Malyuk B.V., Beletskiy A.V., Eismont O.L., Borisov A.V., Kiselev M.G., Esman G.A., Gabets V.L., Alexandrov D.A. The method of penetration of the subchondral bone in the treatment of osteochondritis dissecans of the femoral condyle of the knee joint. Patent RB No. BY 15901 C1 2012.06.30 / Together with the State Institution “Republican Scientific and Practical Center of Traumatology and Orthopedics” and BNTU.

Patent for invention No. 2696501 Antihypoxic substance. Patentee Federal State Budgetary Educational Institution of Higher Education “Smolensk State Medical University” of the Ministry of Health of the Russian Federation (RU). Authors: Evseev Andrey Viktorovich (RU), Surmenev Dmitry Viktorovich (RU), Belenky Albert Eduardovich (RU), Parfyonov Edgar Andreevich (RU), Brook Tatyana Mikhailovna (RU), Pereverzev Vladimir Alekseevich (BY), Evseeva Marina Anatolievna (RU) ... Application No. 201907842. A priority of invention on March 19, 2019. The date of state registration in the State Register of Inventions of the Russian Federation is August 2, 2019. The exclusive right to an invention expires on March 19, 2039. Published on 08/02/2019 Byull. No. 22.

The most important monographs

• Thyroid gland. Fundamental aspects. Ed. A. I. Kubarko, S. Yamashita. Minsk - Nagasaki, Omura pr., 1998, 368 p.
• Thyroid gland in children. Ed. A. I. Kubarko, S. Yamashita, T. Foley. Minsk - Nagasaki, Omura pr., 2002, 450 p.
• Vision (neurophysiological and neuro-ophthalmological aspects). Volume 1 and Volume 2. Neural mechanisms of control of installation and eye movements and their disturbances in diseases of the nervous system. - Minsk, BSMU, 2009. - 352p. / A.I.Kubarko, S.A. Likhachev, N.P. Kubarko
• Radiation and Chernobyl: Cardiomyocytes and the regulation of their functions. Moscow: Belarusian Science, 2008. - 279 p. / K. Ya Bulanova, L. M. Lobanok, E. F. Konoplya
• Pereverzev V.A. Fungoadaptogens: sources of production, biological activity, mechanisms of action, prospects for production. Minsk: BSMU, 2003
• M.O. Welcome, Yu.E. Razvodovsky, E.V. Pereverzev, V.A. Pereverzev The state of cognitive functions among medical students of Belarus with different attitudes to alcohol / ed. V.A. Pereverzev. - Minsk: BSMU, 2013. - 167 p.
• M.O. Welcome, V.A. Pereverzev. Basal Ganglia and the Error Monitoring and Processing System: How Alcohol Modulates the Error Monitoring and Processing Capacity of the Basal Ganglia. // Basal Ganglia - An Integrative View, Fernando A. Barrios, and Clemens Bauer, Editors. InTech, Croatia, January 02, 2013. - 116 p.
• M.O. Welcome and V.A. Pereverzev. Glycemia and Memory (Pp. 113-130). In: Glucose Homeostasis, Leszek Szablewski, Editor, ISBN 978-953-51-1618-9, InTech, 174 pages, June 18, 2014. DOI: 10.5772 / 57190. http://www.intechopen.com/books/glucose-homeostasis.
• Welcome, M.O. [et al.] Alcohol, cognitive function, and glucose homeostasis. Monograph / ed. V.A. Pereverzev // M.O. Welcome, Yu.E. Razvodovsky, N.E. Mastorakis. - LAP (Lamdert Academic Publisheng): Saarbrucken / Deutchland, 2015 .-- 100 p. ISBN 978-3-659-35989-7.
• Physiology. A textbook for students of dental faculties of medical universities / N. A. Agadzhanyan, N. A. Barbarash, M. D. Berg,…. A. I. Kubarko, ... V. A. Pereverzev and others / Ed. V. M. Smirnova. - 2nd ed., Rev. and add. - M.: LLC “Publishing House” Medical Information Agency ”, 2016. - 576 p.
• Physiology: Textbook for students of medical and pediatric faculties / N. A. Barbarash, ... A. I. Kubarko, ... V. A. Pereverzev, ... V. N. Yakovlev / Ed. V. M. Smirnov, V. A. Pravdivtsev, D. S. Sveshnikov. - 5th ed., Rev. and add. - Moscow: LLC “Publishing House” Medical Information Agency ”, 2017. - 512 p.
• Signaling mechanisms of regulation of physiological functions / Ed. : V. V. Lysak, A. I. Kubarko, L. M. Lobanok, V. A. Pereverzev and others / Minsk: RIVSH, 2007. - 346 p .; Minsk: BSU, 2012 .-- 172 p .; Minsk: BSU, 2017 .-- 144 p.
• Korzun, D.L. The role of game means of training for improving the physical condition of children (on the example of young football players): monograph / D.L. Korzun, V.A. - Beau Bassin-Rose Hill : LAP LAMBERT Academic Publishing, 2018. - 97 p.
• Sweet-Taste Receptor Signaling Network and Low-Calorie Sweeteners / M. O. Welcome, N. E. Mastoracis, V. A. Pereverzev // Sweeteners, 2018.
• Physiology: Textbook for students of medical and pediatric faculties / N. A. Barbarash, ... A. I. Kubarko, ... V. A. Pereverzev, ... V. N. Yakovlev / Ed. V. M. Smirnov, D. S. Sveshnikova, A. E. Umryukhina. - 6th ed., Rev. and add. - Moscow: LLC “Publishing House” Medical Information Agency ”, 2019. - 520 p.